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Date of Award
Master of Science (MS)
James H. MeMechan
A method for the preparation of 2-amino-4-phenylthiazoles and its derivatives has been performed. Considering that some previous methods were time consuming, a way has been found to prepare these compounds in reasonable amounts of time. The need of finding a convenient way of brominating acetophenones was investigated. The use of selective bromination with copper (II) bromide offered a convenient method so that compounds could be brominated without the need of isolating the lachromatory products. The products obtained from this type of bromination were then reacted with thiourea to arrive at the aminothiazole.
Copyright 1972 Eddie Suazo
Suazo, Eddie, "The Study and Synthesis of Aminothiazoles" (1972). Master's Theses. 1370.