![Master's Theses](../../assets/md5images/b073eef2c231780838431e1c53638883.jpg)
Department
Chemistry
Degree Name
Master of Science (MS)
Abstract
Two methods for the preparation of [gamma]-pyronocoumarins have been performed; the ring closure of an o- hydroxy- [beta] - ketoacetylcoumarln and the Kostanecki-Robinson reaction of an o-hydroxy-acetylcoumarln. The [beta] - ketoacetyl route was the desired route. The use of dimethylsulfoxide in the Claisen condensation and the Baker-Venkataraman rearrangement offered a convenient method for the cinnamoyl and [beta] - diketo derivative syntheses. The [alpha] -pyrone ring of the coumarin was found to be stable in the basic dimethylsulfoxide media which was used for the rearrangement and condensation. Under other mild, basic conditions, the [alpha] -pyrone ring exhibited the same stability. A brief study was made of the C- acetylation of phenols and hydroxycoumarins with acetic anhydride catalyzed by boron trifluoride.
Advisor
James H. MeMechan
Date of Award
Spring 1967
Document Type
Thesis - campus only access
Recommended Citation
Horinek, Ronald Louis, "Some Aspects of Pyrone Synthesis and Stability" (1967). Master's Theses. 1061.
DOI: 10.58809/RHWT6965
Available at:
https://scholars.fhsu.edu/theses/1061
Rights
© The Author(s)
Comments
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